Effect of Enamel Caries Lesion Baseline Severity on Fluoride Dose-Response

Effect of Enamel Caries Lesion Baseline Severity on Fluoride Dose-Response

This study aimed to investigate the effect of enamel caries lesion baseline severity on fluoride dose-response under pH cycling conditions. Early caries lesions were created in human enamel specimens at four different severities (8, 16, 24, and 36 h). Lesions were allocated to treatment groups (0, 83, and 367 ppm fluoride as sodium fluoride) based on Vickers surface microhardness (VHN) and pH c...

In vitro effect of fluoride oral hygiene tablets on artificial caries lesion formation and remineralization in human enamel

Effect of fluoride toothpastes on enamel demineralization

BACKGROUND It was the aim of this study to investigate the effect of four different toothpastes with differing fluoride compounds on enamel remineralization. METHODS A 3 x 3 mm window on the enamel surface of 90 human premolars was demineralized in a hydroxyethylcellulose solution at pH 4.8. The teeth were divided into 6 groups and the lower half of the window was covered with varnish serving...

In situ protocol for the determination of dose-response effect of low-fluoride dentifrices on enamel remineralization

UNLABELLED No in situ protocol has assessed the dose-response effects of fluoride dentifrices involving low-fluoride formulations. OBJECTIVE To assess the ability of an in situ remineralization model in determining dose-response effects of dentifrices containing low fluoride concentrations ([F]) on bovine enamel. MATERIAL AND METHODS Volunteers wore palatal appliances containing demineraliz...

In situ fluoride response of caries lesions with different mineral distributions at baseline.

The present in situ study investigated the fluoride response of caries lesions with similar mineral loss but two distinct mineral distributions (low- and high-'R', calculated as the ratio of mineral loss to lesion depth). Sixteen subjects wore eight gauze-covered enamel specimens with preformed lesions placed buccally on their mandibular partial dentures for periods up to 4 weeks. The participa...